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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM243244'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 1


(Homo sapiens (human))
BDBM243244
PNG
((r)-n-(1-((2-fluorophenyl)sulfonyl)piperidin-3-yl)...)
Show SMILES CC1(C)N(Cc2nc(NC3CCOCC3)ncc12)C(=O)N[C@@H]1CCCN(C1)S(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C25H33FN6O4S/c1-25(2)19-14-27-23(28-17-9-12-36-13-10-17)30-21(19)16-32(25)24(33)29-18-6-5-11-31(15-18)37(34,35)22-8-4-3-7-20(22)26/h3-4,7-8,14,17-18H,5-6,9-13,15-16H2,1-2H3,(H,29,33)(H,27,28,30)/t18-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a7.5n/a



Novartis AG

US Patent


Assay Description
Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...


US Patent US9546173 (2017)

More data for this
Ligand-Target Pair