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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM318389'
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318389(US10301317, Example 347 | US9624228, Example 347)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318389(US10301317, Example 347 | US9624228, Example 347)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent