Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM50094308'
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50094308(CHEMBL3590114)
Affinity DataIC50:  44nMAssay Description:Inhibition of MEK U911-activated ERK2 (unknown origin) using Erktide as substrate preincubated with enzyme for 20 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50094308(CHEMBL3590114)
Affinity DataIC50:  340nMAssay Description:Inhibition of MEK U911-activated ERK2 (unknown origin) using Erktide as substrate preincubated with enzyme for 20 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50094308(CHEMBL3590114)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of ERK2 in human A375 cells harboring B-RAF V600E mutant assessed as decrease in phospho-ERK2 level after 2 hrs by Cellomics ArrayScanTM V...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed