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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10' and Ligand = 'BDBM92524'
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM92524(Aminopyrazole inhibitor, 3576)
Affinity DataIC50:  7nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM92524(Aminopyrazole inhibitor, 3576)
Affinity DataIC50:  7nMAssay Description:Inhibition of JNK3 (unknown origin) by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Rattus norvegicus)
Eberhard Karls Universit£T T£Bingen

Curated by ChEMBL
LigandPNGBDBM92524(Aminopyrazole inhibitor, 3576)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of JNK3-mediated c-jun phosphorylation in rat INS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed