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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM330276'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 12


(Homo sapiens (Human))
BDBM330276
PNG
(1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)- 3-...)
Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc(Cl)cc3C)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C36H34ClN7O2/c1-22-10-13-25(14-11-22)44-32(21-31(43-44)36(3,4)5)41-35(45)40-29-16-17-30(27-9-7-6-8-26(27)29)46-33-18-19-38-34(42-33)39-28-15-12-24(37)20-23(28)2/h6-21H,1-5H3,(H,38,39,42)(H2,40,41,45)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a>1.58E+4n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr...


US Patent US9724347 (2017)

More data for this
Ligand-Target Pair