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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM330291'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 12


(Homo sapiens (Human))
BDBM330291
PNG
(1-(3-(tert-butyl)-1-(4-methoxyphenyl)-1H- pyrazol-...)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc(O)cc3)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C35H33N7O4/c1-35(2,3)30-21-31(42(41-30)23-11-15-25(45-4)16-12-23)39-34(44)38-28-17-18-29(27-8-6-5-7-26(27)28)46-32-19-20-36-33(40-32)37-22-9-13-24(43)14-10-22/h5-21,43H,1-4H3,(H,36,37,40)(H2,38,39,44)
PDB
MMDB

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US Patent
n/an/a 264n/an/an/an/an/an/a



Respivert, Ltd.

US Patent


Assay Description
The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), were evaluated in a similar fashion to that descr...


US Patent US9724347 (2017)

More data for this
Ligand-Target Pair