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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12' and Ligand = 'BDBM342107'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 12


(Homo sapiens (Human))
BDBM342107
PNG
(3-((4-((4-(3-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5...)
Show SMILES COCCOCCOCCNC(=O)c1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C)C(C)(C)C)c4ccccc34)n2)cc(c1)C#C
Show InChI InChI=1S/C39H44N8O6/c1-7-26-22-27(36(48)40-16-17-51-20-21-52-19-18-50-6)24-28(23-26)42-37-41-15-14-35(45-37)53-32-13-12-31(29-10-8-9-11-30(29)32)43-38(49)44-34-25-33(39(2,3)4)46-47(34)5/h1,8-15,22-25H,16-21H2,2-6H3,(H,40,48)(H,41,42,45)(H2,43,44,49)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 11n/an/an/an/an/an/a



TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED

US Patent


Assay Description
p38 MAPKγ: The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashio...


US Patent US9771353 (2017)


BindingDB Entry DOI: 10.7270/Q2HQ4219
More data for this
Ligand-Target Pair