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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12 (p38MAPgamma)' and Ligand = 'BDBM334317'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 12 (p38MAPgamma)


(Homo sapiens (Human))
BDBM334317
PNG
(1-(3-(tert-Butyl)-1-(6-methoxypyridin-3-yl)-1H-pyr...)
Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cccc(c3)C#N)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C35H31N9O3/c1-35(2,3)29-19-30(44(43-29)24-12-15-31(46-4)38-21-24)41-34(45)40-27-13-14-28(26-11-6-5-10-25(26)27)47-32-16-17-37-33(42-32)39-23-9-7-8-22(18-23)20-36/h5-19,21H,1-4H3,(H,37,39,42)(H2,40,41,45)
PDB
MMDB

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Article
US Patent
n/an/a 316n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9732063 (2017)


Article DOI: 10.1021/jm060978s
More data for this
Ligand-Target Pair