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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12 (p38MAPgamma)' and Ligand = 'BDBM334328'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 12 (p38MAPgamma)


(Homo sapiens (Human))
BDBM334328
PNG
(3-((4-((4-(3-(3-Isopropyl-1-(p-tolyl)-1H-pyrazol-5...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)C)c4ccccc34)n2)cc(OS(C)(=O)=O)c1
Show InChI InChI=1S/C36H35N7O6S/c1-22(2)31-21-33(43(42-31)25-12-10-23(3)11-13-25)40-36(44)39-30-14-15-32(29-9-7-6-8-28(29)30)48-34-16-17-37-35(41-34)38-24-18-26(47-4)20-27(19-24)49-50(5,45)46/h6-22H,1-5H3,(H,37,38,41)(H2,39,40,44)
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 422n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9732063 (2017)

More data for this
Ligand-Target Pair