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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 12 (p38MAPgamma)' and Ligand = 'BDBM334337'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 12 (p38MAPgamma)


(Homo sapiens (Human))
BDBM334337
PNG
(1-(2,3-Dichloro-4-((2-((3-methoxy-5-(2-morpholinoe...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)C)c(Cl)c3Cl)n2)cc(OCCN2CCOCC2)c1
Show InChI InChI=1S/C37H40Cl2N8O5/c1-23(2)30-22-32(47(45-30)26-7-5-24(3)6-8-26)43-37(48)42-29-9-10-31(35(39)34(29)38)52-33-11-12-40-36(44-33)41-25-19-27(49-4)21-28(20-25)51-18-15-46-13-16-50-17-14-46/h5-12,19-23H,13-18H2,1-4H3,(H,40,41,44)(H2,42,43,48)
PDB
MMDB

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US Patent
n/an/a 342n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9732063 (2017)

More data for this
Ligand-Target Pair