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Found 1 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM25989'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Gsk

LigandPNGBDBM25989(N-[(3-methoxyphenyl)methyl]-4-[2-methyl-5-(5-methy...)
Affinity DataKi:  60nM ΔG°:  -40.8kJ/mole IC50:  370nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization assays used GST-tagged enzyme and an ATP-competitive Rhodamine-green labelled fluoroligand. These components were dissolved...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed