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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50314780'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50314780(CHEMBL1091199 | N-Cyclopropyl-3-(1-(2,4-difluoroph...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50314780(CHEMBL1091199 | N-Cyclopropyl-3-(1-(2,4-difluoroph...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50314780(CHEMBL1091199 | N-Cyclopropyl-3-(1-(2,4-difluoroph...)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to P38alpha MAPK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50314780(CHEMBL1091199 | N-Cyclopropyl-3-(1-(2,4-difluoroph...)
Affinity DataKd:  0.310nMAssay Description:Binding affinity to p38alpha by scintillation proximity assayMore data for this Ligand-Target Pair