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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM50392171'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)
Affinity DataIC50:  10nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)
Affinity DataIC50:  19nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)
Affinity DataIC50:  480nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)
Affinity DataIC50:  583nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed