Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 7' and Ligand = 'BDBM50337126'
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ERK5 in human HeLa cells assessed as reduction in EGF-induced ERK5 autophosphorylation pretreated for 1 hr followed by EGF stimulation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd:  670nMAssay Description:In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50337126(2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino...)
Affinity DataKd: >670nMAssay Description:Binding affinity to ERK5 by immobilized ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed