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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50376124'
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376124(CHEMBL261413)
Affinity DataIC50:  10nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50376124(CHEMBL261413)
Affinity DataIC50:  330nMAssay Description:Inhibition of JNK1 in rat H9c2 cells assessed as inhibition of anisomycin-induced cJun phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed