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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM162324'
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162324(US10307427, Compound 15 | US9051313, 15)
Affinity DataIC50:  2.5nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM162324(US10307427, Compound 15 | US9051313, 15)
Affinity DataIC50:  2.5nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In DepthDetails US Patent