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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoacylglycerol acyltransferase type 2 (h-MGAT2)' and Ligand = 'BDBM201484'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201484
PNG
(US9187424, 251)
Show SMILES CS(=O)(=O)CC(=O)NC1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OCC(F)F)cc1
Show InChI InChI=1/C27H26F8N2O6S/c1-44(40,41)15-22(38)36-23-20(16-3-7-19(8-4-16)43-14-21(28)29)13-25(27(33,34)35,37-24(23)39)17-5-9-18(10-6-17)42-12-2-11-26(30,31)32/h3-10,21H,2,11-15H2,1H3,(H,36,38)(H,37,39)
UniProtKB/SwissProt

antibodypedia
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US Patent
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair