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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoacylglycerol acyltransferase type 2 (h-MGAT2)' and Ligand = 'BDBM201507'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201507
PNG
(US9187424, 274)
Show SMILES FC(F)Oc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F
Show InChI InChI=1/C26H22F9N5O3/c27-19-12-16(42-11-3-1-2-10-25(30,31)32)8-9-18(19)24(26(33,34)35)13-17(14-4-6-15(7-5-14)43-23(28)29)20(22(41)36-24)21-37-39-40-38-21/h4-9,12,23H,1-3,10-11,13H2,(H,36,41)(H,37,38,39,40)
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US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair