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Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoacylglycerol acyltransferase type 2 (h-MGAT2)' and Ligand = 'BDBM201540'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201540
PNG
(US9187424, 307)
Show SMILES CCCCCCC#Cc1ccc(cc1F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(OC(F)F)cc1)C(F)(F)F
Show InChI InChI=1/C28H25F6N5O2/c1-2-3-4-5-6-7-8-18-9-12-19(15-22(18)29)27(28(32,33)34)16-21(17-10-13-20(14-11-17)41-26(30)31)23(25(40)35-27)24-36-38-39-37-24/h9-15,26H,2-6,16H2,1H3,(H,35,40)(H,36,37,38,39)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)

More data for this
Ligand-Target Pair