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Found 3 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM449069'
TargetMu-type opioid receptor(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi:  4.75E+3nMAssay Description:For a primary screen of selected molecules, binding to μOR was assessed by measuring competition against the radioligand 3H-diprenorphine (3H-DPN). ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi:  4.75E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM449069(US10702498, Compound 10 | US11484525, Compound 10)
Affinity DataKi: <5.00E+4nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In DepthDetails US Patent