Found 20 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM10759' TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 5.80E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M1 receptor expressed in HEK293T cell membranes after 1 hr by liqu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 1.26E+4nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 1.35E+4nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M1 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 2.29E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M1 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 2.30E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human recombinant muscarinic M1 receptor expressed in CHO-FlpIn cells after 6 hrs by liquid scintillati...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataIC50: 135nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in HEK293T cells co-expressing Galpha subunit and PLC-beta3 by split luciferase complement...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKd: 1.74E+4nMAssay Description:Binding affinity to muscarinic M1 acetylcholine receptor (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 26nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 770nMAssay Description:Activation of M1-ACh receptor-FLASH/CFP expressed in HEK293 cells assessed as FRET signalMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 372nMAssay Description:Partial agonist activity at human muscarinic M1 acetylcholine receptor expressed in CHO cells assessed as increase in IP1 accumulation incubated for ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human m1 muscarinic acetylcholine receptor expressed in HEK293 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 620nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M1 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 2.00E+4nMAssay Description:Agonistic activity against M1 muscarinic receptor expressed in NIH 3T3 cells.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 47nMAssay Description:Agonist activity at recombinant human muscarinic M1 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 47nMAssay Description:Agonist activity at recombinant human muscarinic M1 receptor expressed in CHO cells assessed as upregulation in ERK1/2 phosphorylation after 5 mins b...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataKd: 1.74E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 acetylcholine receptor expressed in CHO cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
University Of Arizona
Curated by PDSP Ki Database
University Of Arizona
Curated by PDSP Ki Database
Affinity DataEC50: 617nMAssay Description:Agonist activity at Gq/11 coupled recombinant human muscarinic M1 AChR expressed in CHO-FlpIn cells assessed as IP-one accumulation after 40 mins by ...More data for this Ligand-Target Pair
