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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM360055'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360055
PNG
(5-Fluoro-3'- | US9828339, Example 21)
Show SMILES CN1CCCC1CCOC(=O)Nc1ccc(F)cc1-c1ccccc1
Show InChI InChI=1/C20H23FN2O2/c1-23-12-5-8-17(23)11-13-25-20(24)22-19-10-9-16(21)14-18(19)15-6-3-2-4-7-15/h2-4,6-7,9-10,14,17H,5,8,11-13H2,1H3,(H,22,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
2.25n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair