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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM360101'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360101
PNG
(2-(1-Methyl- | US9828339, Example 53)
Show SMILES CN1CCCC1CCOC(=O)Nc1ccc(F)cc1-c1ccc(F)c(Cl)c1
Show InChI InChI=1/C20H21ClF2N2O2/c1-25-9-2-3-15(25)8-10-27-20(26)24-19-7-5-14(22)12-16(19)13-4-6-18(23)17(21)11-13/h4-7,11-12,15H,2-3,8-10H2,1H3,(H,24,26)
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UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
1.34n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair