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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM360144'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360144
PNG
((R)-pyrrolidin-3-ylmethyl [1,1'-biphenyl]-2-ylcarb...)
Show SMILES O=C(Nc1ccccc1-c1ccccc1)OC[C@@H]1CCNC1
Show InChI InChI=1S/C18H20N2O2/c21-18(22-13-14-10-11-19-12-14)20-17-9-5-4-8-16(17)15-6-2-1-3-7-15/h1-9,14,19H,10-13H2,(H,20,21)/t14-/m1/s1
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
4.62n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair