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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM360198'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360198
PNG
((R)-(1-methyl- | US9828339, Example 114)
Show SMILES CN1CC[C@@H](COC(=O)Nc2ccccc2-c2ccc(F)cc2)C1
Show InChI InChI=1S/C19H21FN2O2/c1-22-11-10-14(12-22)13-24-19(23)21-18-5-3-2-4-17(18)15-6-8-16(20)9-7-15/h2-9,14H,10-13H2,1H3,(H,21,23)/t14-/m1/s1
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
4.23n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair