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Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM360212'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM360212
PNG
((S)-(1-methyl- | US9828339, Example 128)
Show SMILES CN1CC[C@H](COC(=O)Nc2ccc(F)cc2-c2ccc(Cl)c(Cl)c2)C1
Show InChI InChI=1S/C19H19Cl2FN2O2/c1-24-7-6-12(10-24)11-26-19(25)23-18-5-3-14(22)9-15(18)13-2-4-16(20)17(21)8-13/h2-5,8-9,12H,6-7,10-11H2,1H3,(H,23,25)/t12-/m0/s1
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PC cid
PC sid
UniChem
Article
US Patent
3.41n/an/an/an/an/an/an/an/a



DONG-A ST CO., LTD

US Patent


Assay Description
Cell membrane proteins (Perkin Elmer) wherein human muscarinic M3 receptor was overexpressed, [3H]-methyl scopolamine and test compounds in various c...


US Patent US9828339 (2017)


Article DOI: 10.1021/jm070556y
More data for this
Ligand-Target Pair