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Found 3 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM50238827'
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50238827(CHEMBL4064328)
Affinity DataIC50:  3.14E+5nMAssay Description:Inhibition of MPO in human neutrophils assessed as reduction in HOCl production preincubated for 30 mins followed by H2O2 addition by APF staining ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed