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Found 3 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-5, mitochondrial' and Ligand = 'BDBM50358043'
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of human Sirt5 desuccinylation activity using SKEYFS-succinylLys-QK as substrate measured for 15 mins by MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  9.78E+4nMAssay Description:Inhibition of human Sirt5 deacetylation activity using FKRGVL-acetylLys-EYGVKV as substrate measured for 15 mins by MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
University Of Bayreuth

Curated by ChEMBL
LigandPNGBDBM50358043(CHEMBL1794051 | GW-5074)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of human Sirt5 deacetylation activity using SKEYFS-acetylLys-QK as substrate measured for 15 mins by MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed