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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NEDD8-conjugating enzyme UBE2F' and Ligand = 'BDBM320971'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NEDD8-conjugating enzyme UBE2F


(Homo sapiens (Human))
BDBM320971
PNG
(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Show SMILES CCNc1cc(F)c(C#Cc2cn([C@@H]3O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]3O)c3ncnc(N)c23)c(F)c1
Show InChI InChI=1S/C21H23F2N7O5S/c1-2-26-11-5-13(22)12(14(23)6-11)4-3-10-8-30(20-16(10)19(24)27-9-28-20)21-18(32)17(31)15(35-21)7-29-36(25,33)34/h5-6,8-9,15,17-18,21,26,29,31-32H,2,7H2,1H3,(H2,24,27,28)(H2,25,33,34)/t15-,17-,18-,21-/m1/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...


US Patent US10174040 (2019)

More data for this
Ligand-Target Pair