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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NEDD8-conjugating enzyme UBE2F' and Ligand = 'BDBM320986'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NEDD8-conjugating enzyme UBE2F


(Homo sapiens (human))
BDBM320986
PNG
(4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(sulfamo...)
Show SMILES COc1ccccc1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12
Show InChI InChI=1S/C20H22N6O6S/c1-31-13-5-3-2-4-11(13)6-7-12-9-26(19-15(12)18(21)23-10-24-19)20-17(28)16(27)14(32-20)8-25-33(22,29)30/h2-5,9-10,14,16-17,20,25,27-28H,8H2,1H3,(H2,21,23,24)(H2,22,29,30)/t14-,16-,17-,20-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.30n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...


US Patent US10174040 (2019)

More data for this
Ligand-Target Pair