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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NEDD8-conjugating enzyme UBE2F' and Ligand = 'BDBM320993'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NEDD8-conjugating enzyme UBE2F


(Homo sapiens (human))
BDBM320993
PNG
(4-Amino-5-[2-(4-cyano-2,6-difluoro-phenyl)ethynyl]...)
Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)C#N)c12)[C@@H]1O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C20H17F2N7O5S/c21-12-3-9(5-23)4-13(22)11(12)2-1-10-7-29(19-15(10)18(24)26-8-27-19)20-17(31)16(30)14(34-20)6-28-35(25,32)33/h3-4,7-8,14,16-17,20,28,30-31H,6H2,(H2,24,26,27)(H2,25,32,33)/t14-,16-,17-,20-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.80n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...


US Patent US10174040 (2019)

More data for this
Ligand-Target Pair