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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NEDD8-conjugating enzyme UBE2F' and Ligand = 'BDBM321041'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NEDD8-conjugating enzyme UBE2F


(Homo sapiens (human))
BDBM321041
PNG
(4-Amino-5-[2-[2,6-difluoro-4-[(3S)-3-hydroxypyrrol...)
Show SMILES Nc1ncnc2n(cc(C#Cc3c(F)cc(cc3F)N3CC[C@H](O)C3)c12)[C@@H]1C[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C24H27F2N7O5S/c25-17-6-14(32-4-3-15(34)10-32)7-18(26)16(17)2-1-12-9-33(24-20(12)23(27)29-11-30-24)19-5-13(21(35)22(19)36)8-31-39(28,37)38/h6-7,9,11,13,15,19,21-22,31,34-36H,3-5,8,10H2,(H2,27,29,30)(H2,28,37,38)/t13-,15+,19-,21-,22+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.20n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
A purified NAE (heterodimer of APPBP1 and UBA3) solution was prepared in the following manner. The human APPBP1 gene (NCBI Reference Sequence number:...


US Patent US10174040 (2019)

More data for this
Ligand-Target Pair