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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NS3 serine protease (NS3)' and Ligand = 'BDBM347261'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NS3 serine protease (NS3)


(Hepatitis C Virus (Virus))
BDBM347261
PNG
(US10202411, Compound 307)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](CO)[C@H]1O
Show InChI InChI=1S/C11H18N5O13P3/c12-9-7-10(14-3-13-9)16(4-15-7)11-8(18)5(1-17)6(27-11)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h3-6,8,11,17-18H,1-2H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21)/t5-,6-,8-,11-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



IDENIX PHARMACEUTICALS LLC

US Patent


Assay Description
Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...


US Patent US10202411 (2019)

More data for this
Ligand-Target Pair