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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NS3 serine protease (NS3)' and Ligand = 'BDBM347266'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NS3 serine protease (NS3)


(Hepatitis C Virus (Virus))
BDBM347266
PNG
(US10202411, Compound 330)
Show SMILES Nc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](CO)[C@H]3O)c2n1
Show InChI InChI=1S/C11H19N6O13P3/c12-8-6-9(16-11(13)15-8)17(3-14-6)10-7(19)4(1-18)5(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h3-5,7,10,18-19H,1-2H2,(H,23,24)(H,25,26)(H2,20,21,22)(H4,12,13,15,16)/p-3/t4-,5-,7-,10-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a 625n/an/an/an/an/an/a



IDENIX PHARMACEUTICALS LLC

US Patent


Assay Description
Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...


US Patent US10202411 (2019)

More data for this
Ligand-Target Pair