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Found 19 Enz. Inhib. hit(s) with Target = 'NT-3 growth factor receptor' and Ligand = 'BDBM158154'
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  1nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <1nMAssay Description:Kinase assay: After the buffer was prepared, the enzyme was mixed with different concentrations of pre-diluted compounds in duplex, and allowed to st...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human TEL (336 residues) fused-TRKC (454 to 825 residues) (unknown origin) expressed in mouse BAF3 cells assessed as cell growth inhibi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TRKC (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TrkC (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of TRKC (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human TRKC incubated for 90 mins by selectscreen kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))
Shenzhen Targetrx

US Patent
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)
Affinity DataIC50: <10nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed