Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50105264'
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataKi:  1.70nMAssay Description:50% inhibitory activity against enkephalinase purified from rat kidney with [3H]D-Ala2-Leu-enkephalin (20 nM) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataKi:  1.70nMAssay Description:Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]Ala2-Leu-enkephalin binding to Neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)
Affinity DataIC50:  46nMAssay Description:Inhibitory activity against rabbit kidney neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article