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Found 2 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM141887'
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141887(US8921410, Table 2 Compound 25)
Affinity DataKi:  5.20nM ΔG°:  -46.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141887(US8921410, Table 2 Compound 25)
Affinity DataKi:  7.5nM ΔG°:  -45.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent