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Found 4 Enz. Inhib. hit(s) with Target = 'Neuropeptides B/W receptor type 1' and Ligand = 'BDBM50362413'
TargetNeuropeptides B/W receptor type 1(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50362413(CHEMBL1940538)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [125]-hNPW23 from mouse NPBWR1 expressed in CHO-K1 cells membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptides B/W receptor type 1(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50362413(CHEMBL1940538)
Affinity DataIC50:  4.60nMAssay Description:Antagonist activity at mouse NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50362413(CHEMBL1940538)
Affinity DataIC50:  35nMAssay Description:Displacement of [125]-hNPW23 from human NPBWR1 expressed in CHO-K1 cells membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50362413(CHEMBL1940538)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed