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Found 2 Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM449142'
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449142(Thieno[2,3-c]pyridine-2- carboxylic acid 4-(1- oxe...)
Affinity DataIC50:  4.27nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM449142(Thieno[2,3-c]pyridine-2- carboxylic acid 4-(1- oxe...)
Affinity DataIC50:  4.30nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent