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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM50011179'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))
BDBM50011179
PNG
(CHEMBL3260317)
Show SMILES COCC(=O)N(CCC(C)C)c1ncc(s1)C(=O)NCCCn1ccnc1
Show InChI InChI=1S/C18H27N5O3S/c1-14(2)5-9-23(16(24)12-26-3)18-21-11-15(27-18)17(25)20-6-4-8-22-10-7-19-13-22/h7,10-11,13-14H,4-6,8-9,12H2,1-3H3,(H,20,25)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 0.412n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human C-terminally His-tagged NAMPT by TR-FRET assay in presence of PRPP


Citation and Details

Article DOI: 10.1021/ml500046t
BindingDB Entry DOI: 10.7270/Q25X2BF6
More data for this
Ligand-Target Pair