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Found 2 Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM50447569'
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50447569(CHEMBL3112697)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length C-terminal His6-tagged human NAMPT expressed in Escherichia coli Rosetta (DE3) cells using PRPP/NAM as substrate/cofactor p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50447569(CHEMBL3112697)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to N-terminal His6-tagged/biotinylated C-terminal Avi-tagged human NAMPT (2 to 491) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed