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Found 5 Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50147746'
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147746(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-indol-2-on...)
Affinity DataKi:  201nMAssay Description:Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147746(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-indol-2-on...)
Affinity DataKi:  201nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147746(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-indol-2-on...)
Affinity DataKi:  201nMAssay Description:Displacement of [3H] N/OFQ from human nociceptin receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147746(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-indol-2-on...)
Affinity DataEC50:  174nMAssay Description:Agonist activity at human nociceptin receptor transfected in CHO cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Sri International

Curated by ChEMBL
LigandPNGBDBM50147746(1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-indol-2-on...)
Affinity DataEC50:  174nMAssay Description:Concentration required for stimulation of [35S]-GTP-gammaS, binding to human Nociceptin receptor in cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed