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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM339050'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM339050(US10201546, Example 12c)
Affinity DataIC50:  330nMAssay Description:For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM339050(US10201546, Example 12c)
Affinity DataKd:  63nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent