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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM341785'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))
BDBM341785
PNG
((1R,2S,4s)-4-((4-fluorophenyl)sulfonyl)-4-(4-(1,1,...)
Show SMILES O[C@H]1C[C@](C[C@H]1O)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C20H17F7O5S/c21-13-5-7-14(8-6-13)33(31,32)17(9-15(28)16(29)10-17)11-1-3-12(4-2-11)18(30,19(22,23)24)20(25,26)27/h1-8,15-16,28-30H,9-10H2/t15-,16+,17-
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 53n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...


US Patent US9771320 (2017)

More data for this
Ligand-Target Pair