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Found
1
Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM359506'
Target
Nuclear receptor ROR-gamma
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM359506
(US10221142, Example 9A)
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Affinity Data
IC50: 1.60nM
Assay Description:
The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...
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Target Info
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Reactome pathway
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antibodypedia
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Ligand Info
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US Patent
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