Found 8 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50445895' 
Affinity DataIC50: 10nMAssay Description:Inverse agonist activity at biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-bi...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human recombinant N-terminally 6xHis-tagged RORgamma ligand binding domain (unknown origin) expressed in Escherichia coli...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inverse agonist activity at RORgammaT (unknown origin) by M1H assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of APC-labeled RORgammat receptor ligand binding domain (unknown origin) after 1 hr by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-bip...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inverse agonist activity at RORgammaT (unknown origin) by Jurkat cell based luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of RORgammat receptor ligand binding domain in mouse spleen CD4+ T cells assessed as inhibition of IL-17 production after 3 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 251nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
