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Found 2 Enz. Inhib. hit(s) with Target = 'Opioid growth factor receptor-like protein 1' and Ligand = 'BDBM220361'
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM220361(US9290488, B11a(ii))
Affinity DataKi:  12.1nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOpioid growth factor receptor-like protein 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM220361(US9290488, B11a(ii))
Affinity DataEC50:  6.54nMpH: 7.4 T: 2°CAssay Description:ORL-1 membrane solution was prepared by sequentially adding final concentrations of 0.066 μg/μL ORL-1 membrane protein, 10 μg/mL saponin, 3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent