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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 1' and Ligand = 'BDBM373192'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Orexin receptor type 1


(Homo sapiens (Human))
BDBM373192
PNG
(US9896452, Example 52 | rac-N-((5,5-difluoro-1-(5-...)
Show SMILES Cc1nc(C(=O)N2CC(F)(F)CCC2CNC(=O)c2cccc3cccnc23)c(s1)-c1cccc(F)c1
Show InChI InChI=1/C27H23F3N4O2S/c1-16-33-23(24(37-16)18-6-2-8-19(28)13-18)26(36)34-15-27(29,30)11-10-20(34)14-32-25(35)21-9-3-5-17-7-4-12-31-22(17)21/h2-9,12-13,20H,10-11,14-15H2,1H3,(H,32,35)
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PC sid
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US Patent
n/an/a 1n/an/an/an/an/an/a



EOLAS THERAPEUTICS, INC.

US Patent


Assay Description
Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...


US Patent US9896452 (2018)

More data for this
Ligand-Target Pair