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Found 3 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM175203'
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM175203(US9115117, 112 | US9611251, 112)
Affinity DataKi:  562nMAssay Description:HEK293 stably expressing human orexin 2 receptor (Genebank accession numberNM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022) , 10%...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM175203(US9115117, 112 | US9611251, 112)
Affinity DataKi:  562nMAssay Description:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM175203(US9115117, 112 | US9611251, 112)
Affinity DataKi:  562nMAssay Description:Antagonist activity at human orexin-2 receptor expressed in human PFSK-1 cells assessed as inhibition of orexin-B-induced Ca2+ release preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed