BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM317570'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))
BDBM317570
PNG
(3-methoxy-2- {methyl[(3R,6R)-6- methyl-1-{[2-(2H-1...)
Show SMILES COc1c(ccnc1N(C)[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccsc1-n1nccn1)C#N
Show InChI InChI=1S/C21H23N7O2S/c1-14-4-5-16(26(2)19-18(30-3)15(12-22)6-8-23-19)13-27(14)20(29)17-7-11-31-21(17)28-24-9-10-25-28/h6-11,14,16H,4-5,13H2,1-3H3/t14-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 39n/an/an/an/an/an/a



MERCK SHARP & DOHME CORP.

US Patent


Assay Description
FLIPR Ca2+ Flux Assay- (Okumura et al., Biochem. Biophys. Res. Comm. 280:976-981, 2001). In a typical experiment the OX1 and OX2 receptor antagonisti...


US Patent US9624197 (2017)

More data for this
Ligand-Target Pair